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Tuesday, 10 Sep 2019 06:13 pm

Rising Adoption of CRISPR Cas9 Technology Fueling the global market of Genome Editing

The CRISPR Cas9 technology is widely used across the biotechnology industry for the applications of the genome editing. The scientists and the companies around the world are conducting researches for the use of the CRISPR for various its applications. The start-up companies are extensively working for the CRISPR applications. For instance, eGenesis is involved for the application of CRISPR Cas 9 technology to the field of human therapeutics.

By SMN Bureau

According to a new market research study titled ‘Genome Editing Market to 2025 – Global Analysis and Forecasts by Technology, Application and End User. The global genome editing market is estimated to account for US$ 10,691.0 Mn by 2025 as compared to US$ 3,210.1 Mn in 2017, growing at a CAGR of 17.0% during the forecast period from 2018 to 2025. The report highlights the trends prevalent in the global genome editing market and the factors driving the market along with those fact as restraint to its growth.

The growth of the market is expected rise due to the trend of usage of the CRISPR Cas9 technology. The CRISPR Cas9 technology is widely used across the biotechnology industry for the applications of the genome editing. The scientists and the companies around the world are conducting researches for the use of the CRISPR for various its applications. The start-up companies are extensively working for the CRISPR applications. For instance, eGenesis is involved for the application of CRISPR Cas 9 technology to the field of human therapeutics. The company is dedicatedly working for reeving the idea of xenotransplantation, or animal-to-human organ transplants. The company aims to grow the human compatible organs inside pigs. As the pig genomes can contain up to several dozen copies of porcine endogenous retroviruses, or PERVs, which can’t be eliminated by breeding alone. The company has successfully multiplexed CRISPR-Cas9 to disrupt all 62 copies of the porcine endogenous retroviruses (PERVs) that resulted in a greater 1000 fold reduction in PERV transmission to human cells in vitro. In addition, Synthetic Genomics is start-up company which has coupled CRISPR to create sustainable energy through manipulating microalgae for sustainable oil production. The company has partnered with Exxon Mobile and have identified 20 transcription factors thought to be negative regulators of lipid production in microalgae. The company has applied CRISPR-Cas9 to insert loss of function mutations in 18 of the 20 genes. The advancement will increase oil production by 200% with the modified microalgae species marking a key advancement in renewable energy biofuels.

The application segment of the genome editing market is classified into genetic engineering, cell line engineering and others. In 2017, cell line engineering segment held the largest share of 48.2% of the market. In addition, the segment is expected to dominate during the coming years owing to the benefits such as optimization of cell lines for the recombinant protein expression and characterization of the protein profile of the genetically modified organisms. The cell line engineering enables to produce various industrial and commercial products that gain much more revenue as the products are produced as per the desired requirement. Similarly, the genetic engineering segment is expected to be the fastest growing application segment for the genome editing market. The cell line engineering market was valued at US$ 1,548.8 Mn in 2017.

Key industry players operating in the field of genome editing across the globe include Transposagen Biopharmaceuticals, Inc., Integrated DNA Technologies, Inc., Thermo Fisher Scientific Inc., GenScript, Lonza, Horizon Discovery Group plc, Sangamo Therapeutics, Inc., New England Biolabs, Editas Medicine, Merck KGaA.

The report segments the global genome editing market as follows:

Global Genome Editing Market – By Technology

  • TALENs
  • CRISPR
  • ZFN
  • Others

Global Genome Editing Market – By Application

  • Genetic Engineering
    • Animal Genetic Engineering
    • Plant Genetic Engineering
  • Cell Line Engineering
  • Others
  • Global Genome Editing Market – By End User
    • Biotechnology & Pharmaceutical Companies
    • Contract Research Organization (CROs)
    • Academic & Government Research Institutes

Global Genome Editing Market – By Geography

  • Nrth America
    • U.S.
    • Canada
    • Mexico
  • Eurpe
    • UK
    • Germany
    • France
  • Asia Pacific (APAC)
    • Japan
    • China
    • India
  • Middle East & Africa (MEA)
    • South Africa
    • Saudi Arabia
    • UAE
  • Suth & Central America (SCAM)
    • Brazil

 


SMN Bureau

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