The global Sanger sequencing service market, based on application, was segmented as, diagnostics, biomarkers and cancer, reproductive health, personalized medicine, forensics, and other applications. In 2018 biomarkers and cancer held the largest share of the market, by application, due to the rising incidence of cancer, increasing the use of cancer biomarkers in drug discovery and diagnostics, and increasing research on cancer biomarkers.
Europe is the second-largest geographic market and is expected to be the second most significant revenue contributor throughout the forecast period. The region has witnessed an increase in research funding and growth of the biotechnology sector, which is expected to offer growth opportunities in the market.
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The major players operating in the Sanger sequencing service market include Microsynth AG, Laragen, Inc., StarSEQ GmbH, Thermo Fisher Scientific, Inc., LGC Biosearch Technologies, Fasteris SA, Quintara Biosciences, GENEWIZ, GenScript, and SciGenom Labs among others. The market of Sanger sequencing service has witnessed various organic developments during recent years. During September 2019, GENEWIZ, a Brooks Life Sciences Company, declared the opening of its European headquarters for its genomics business in Germany. The facility will provide onsite Sanger sequencing and next-generation sequencing services.
The market for Sanger sequencing service is expected to grow owing to factors such as increasing providers for Sanger sequencing services and growing applications of Sanger sequencing. Also, an increase in the number of startup companies for genome analysis is expected to have a positive impact on the growth of the market in the coming years.
Growing Application Of Sanger Sequencing
Sanger sequencing is the superior method for sequencing, and it is a process of incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication. Sanger sequencing is known to provide high accuracy, long-read capabilities, and adaptability to support a diverse range of applications in many research areas. Sanger sequencing is mainly recognized for DNA sequencing and supports applications in RNA sequencing and epigenetic analysis.
In many clinical studies, in different groups of subjects, substantive insights have been made by comparing the primary DNA sequences of genes. For example, As per Thermo Fisher Scientific, a recent study showed that up to 2% of the variants detected by NGS were not reproducible by Sanger sequencing. Therefore, in many clinical studies before a firm conclusion from variants identified by NGS, it should be confirmed by an orthogonal method. Reference materials sequenced by Sanger approaches provide ground truth against which the NGS assay can be benchmarked.
Increasing Number of Start-Up Companies for Genome Analysis
The healthcare industry aims to advanced technology to reduce health problems and to extend the lifespan of human beings. Therefore, international brands, as well as thousands of biotechnology start-ups across the globe, are aiming to contribute to humanity by developing new technologies for the healthcare sector.
Many of the evolving biotechnology and genetics start-ups are using DNA sequencing technologies for various applications. These new emerging companies are offering sequencing services that analyze human and animal genomes. For instance, located in Baltimore, United States, Personal Genome Diagnostics Inc. was founded in 2010 and is involved in genome analysis of human tumors. The company develops a patient-specific analysis of cancer by using sequencing tools and technologies.
The report segments the Global Sanger Sequencing Service Market as follows:
Global Sanger Sequencing Service Market – By Application
Global Sanger Sequencing Service Market – By End User
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